The 10 Best Astragalus Supplements for Maximum Immunity & Longevity
Astragalus has been a trusted herb in Traditional Chinese Medicine for over 2,000 years. Its antioxidant-rich compounds, like flavonoids and polysaccharides, are known to support the immune system, cardiovascular health, and anti-aging processes.
But finding a quality supplement that delivers real benefits isn’t easy. Many brands promise potency, but not all extracts are created equal. Some fall short on purity, while others don’t pack enough active compounds like polysaccharides and flavonoids to offer therapeutic benefits.
After analyzing scientific research, studying thousands of customer reviews, and comparing formulations, we’ve ranked the 10 best astragalus supplements based on potency, purity, and value. Each review below provides detailed insights to help you make a well-informed decision.
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What Is Astragalus & How Does It Work?
Astragalus (Astragalus membranaceus) is an adaptogenic herb that contains polysaccharides, saponins, and flavonoids, which work together to:
✔ Boost immune system function by activating white blood cells (source)
✔ Improve cardiovascular health by reducing oxidative stress (source)
✔ Support anti-aging and longevity through telomere protection (source)
✔ Enhance kidney and liver function by reducing inflammation (source)
✔ Improve energy levels and endurance through its adaptogenic properties (source)
Studies show that polysaccharides in astragalus help regulate the immune response, making it particularly beneficial for autoimmune conditions, respiratory infections, and seasonal immune support.
Different Types of Astragalus Supplements
Before choosing an astragalus supplement, it’s important to understand the different forms and extraction methodsavailable:
1. Whole-Root Powder
- Contains all naturally occurring compounds in astragalus
- Less concentrated than extracts
- Used in capsules, teas, or powders
- Best for holistic, full-spectrum herbal support
2. Extracts (Standardized & Ratios)
- Standardized extracts guarantee a certain percentage of polysaccharides (e.g., 70%)
- Ratio extracts (e.g., 10:1, 20:1, 30:1) concentrate the herb for higher potency
- Best for targeted immune support, anti-aging benefits, and cardiovascular health
3. Liquid Extracts (Tinctures & Phyto-Capsules)
- Faster absorption than capsules or powders
- Can be alcohol-based or glycerin-based
- Best for those with digestive sensitivities or who prefer liquid dosing
4. Combination Formulas
- Blended with other adaptogens (e.g., Schisandra, Rhodiola, or Reishi)
- May enhance stress resistance and overall vitality
- Best for those looking for comprehensive herbal support
Who Should Take Astragalus?
✔ People Looking to Boost Immunity – Supports white blood cells and defends against infections
✔ Athletes & Active Individuals – Increases endurance and recovery
✔ Those with Cardiovascular Concerns – Reduces oxidative stress and promotes heart health
✔ People Seeking Longevity Support – Protects telomeres and slows cellular aging
✔ Individuals with Kidney or Liver Issues – Supports detoxification and reduces inflammation
Who Should Avoid It?
✘ Individuals Taking Immunosuppressants – Astragalus stimulates the immune system, which can interfere with medications for autoimmune diseases
✘ People on Blood Thinners – Astragalus can affect blood clotting
✘ Pregnant or Nursing Women – Limited safety data
How to Choose the Best Astragalus Supplement
When selecting an astragalus supplement, consider these key factors:
1. Extraction Method & Potency
- Whole-root formulas provide full-spectrum benefits
- Extracts with standardized polysaccharides (e.g., 70%) ensure potency
- Higher extraction ratios (e.g., 20:1, 30:1) deliver stronger effects
2. Ingredient Purity
- Look for non-GMO, organic, and third-party tested options
- Avoid fillers, artificial colors, or unnecessary additives
3. Dosage & Servings
- 500–1500mg per day is standard for general wellness
- High-strength extracts (5000mg+ equivalents) require fewer capsules per serving
4. Brand Reputation & Reviews
- Choose brands with transparent sourcing and quality testing
- Read consumer feedback on effectiveness, purity, and safety
Top 10 Best Astragalus Supplements Ranked & Reviewed
1. Double Wood Supplements Astragalus 500mg (180 capsules)
High-Quality Extract with Long-Term Supply
Why It Stands Out:
- Polysaccharide-rich formula – essential for immune response
- 5-month supply (300 capsules per bottle)
- Third-party tested for purity
Double Wood Supplements is a well-reputed brand known for producing clean, potent, and third-party-tested supplements. Their astragalus extract (500mg per capsule) is designed to enhance immune resilience, heart health, and longevity.
One major plus is the high polysaccharide concentration, which is key to astragalus’ immunomodulatory and anti-inflammatory effects. Studies suggest astragalus boosts immune cells like T-cells and natural killer cells, essential for defending against infections (source).
Pros:
✔ Supports T-cell activation, helping strengthen immune defense
✔ No additives, fillers, or GMOs—just pure astragalus extract
✔ Lab-tested and verified for potency
Cons:
✘ Standardized extract strength is not disclosed, leaving some uncertainty on potency
✘ May require multiple capsules per day for higher dosages
Users praise the supplement for its immune-supporting effects, particularly during seasonal changes. Some report improved energy levels and respiratory health. However, those seeking a high-extract potency may prefer a more concentrated formula.
“About an hour after taking the first dose, I noticed a significant increase in my energy levels, and the usual afternoon slump was gone. I’m also finding that I’m less inclined to reach for starchy carbs throughout the day compared to before.”
2. NOW Foods Astragalus Extract 500mg (90 Capsules)
Highly Standardized for Reliable Immune Support
Why It Stands Out:
- Standardized to 70% polysaccharides, ensuring a concentrated dose of active compounds
- GMP-certified and Non-GMO
- Vegan-friendly formula
NOW Foods is a trusted name in the supplement industry, and this astragalus extract is no exception. With a 70% polysaccharide standardization, it delivers a consistent and potent dose aimed at strengthening immune function.
Research suggests astragalus polysaccharides may stimulate macrophages, modulate cytokine activity, and support overall immune function (source). Regular use may help protect against respiratory infections, seasonal illnesses, and oxidative damage.
Pros:
✔ One of the highest standardized polysaccharide contents available
✔ Well-established brand with rigorous quality testing
✔ Vegan, non-GMO, and free from common allergens
Cons:
✘ Only 90 capsules per bottle—may require frequent repurchasing
✘ May not contain the full spectrum of astragalus compounds due to standardization
Users frequently mention experiencing fewer seasonal illnesses after taking this supplement. The standardized extract ensures reliable potency, but some prefer whole-root formulations for a broader range of bioactive compounds.
3. Nutricost Astragalus 550mg (240 Capsules)
Affordable & High-Value Supplement
Why It Stands Out:
- 550mg per capsule, slightly higher than most competitors
- 240-capsule supply—great value for the price
- Gluten-free, soy-free, and non-GMO
For those who want higher doses of astragalus per serving, Nutricost offers an excellent-value supplement with 550mg per capsule. This is ideal for individuals who need consistent immune reinforcement, anti-fatigue benefits, or cardiovascular support.
The bulk packaging (240 capsules) means you won’t need to repurchase frequently, making it a cost-effective long-term option. The brand adheres to strict GMP manufacturing standards, which ensures product purity and quality control.
Pros:
✔ Higher potency per capsule than many competitors
✔ Large bottle ensures a long supply
✔ Third-party tested and GMP-compliant
Cons:
✘ Lacks standardized polysaccharide content
✘ Might not be as potent as concentrated extracts
Many users appreciate its affordability and simplicity, with positive reviews about its immune-boosting and energy-enhancing effects. However, those seeking maximum extract potency may prefer a standardized formula.
4. Purely Holistic Astragalus 5000mg (250 Capsules)
Ultra-Potent 20:1 Extract for Maximum Effectiveness
Why It Stands Out:
- 20:1 extract ratio, meaning each capsule equals 5000mg of raw astragalus root
- 250-capsule supply—lasts over 8 months
- High standardization of 70% polysaccharides
Purely Holistic’s high-strength Astragalus Root Extract is designed for individuals seeking maximum potency with minimal capsule intake. Thanks to the 20:1 extract ratio, this supplement delivers the equivalent of 5000mg of astragalus root per capsule, making it significantly more powerful than standard astragalus powders.
With 70% polysaccharide standardization, this formula prioritizes the immune-boosting, anti-inflammatory, and adaptogenic properties of astragalus. Customers report noticeable improvements in recovery from fatigue, allergy relief, and general immunity when taking this supplement long-term.
Pros:
✔ Superior potency compared to standard whole-root capsules
✔ One of the longest-lasting supplies available
✔ Vegan-friendly and free of unnecessary additives
Cons:
✘ Not suitable for those who prefer raw astragalus powder
✘ Higher price point due to extract concentration
Users who seek strong immune defense and cardiovascular benefits prefer this high-strength extract. Many report better energy levels and improved recovery from seasonal stressors. However, those used to whole-root formulations may find the extract too concentrated.
5. Oregon’s Wild Harvest Astragalus (1125mg Per Serving)
Certified Organic for Clean, Pure Nutrition
Why It Stands Out:
- Certified organic astragalus root—free from pesticides and contaminants
- No artificial additives, gluten, dairy, or soy
- Grown and manufactured in the USA
For those who prioritize organic ingredients and sustainability, Oregon’s Wild Harvest provides high-potency astragalus root capsules made from responsibly sourced plants.
Pros:
✔ Certified organic, ensuring clean and potent astragalus
✔ Free from artificial additives and major allergens
✔ Family-owned company known for high-quality herbal products
Cons:
✘ Whole-root formula may not be as potent as standardized extracts
✘ 1125mg per serving requires multiple capsules
Health-conscious consumers love this pure, organic formula. Many appreciate the brand’s commitment to sustainability and transparency. However, users looking for highly concentrated extracts may find the potency lower compared to standardized formulas.
6. Nature’s Way Astragalus Root (180 Vegan Capsules)
Traditional Herbal Support with Non-GMO Certification
Why It Stands Out:
- Traditional astragalus root formula used for centuries in Chinese medicine
- Non-GMO Project Verified, gluten-free, and dairy-free
- Trusted brand with 50+ years in herbal supplements
Nature’s Way stays true to traditional astragalus without extracts or high-standardization ratios. Instead, it delivers pure, whole-root astragalus powder, ensuring users get all naturally occurring bioactive compounds.
Pros:
✔ Pure, unprocessed astragalus root powder for full-spectrum benefits
✔ Vegan-friendly, non-GMO, and free from artificial ingredients
✔ Reputable brand known for high-quality herbal supplements
Cons:
✘ No standardization means inconsistent polysaccharide content
✘ Requires multiple capsules per serving (3 capsules twice daily)
Many users who prefer natural, whole-herb supplementation appreciate the authenticity of this product. However, those looking for highly concentrated extracts for faster results may opt for Purely Holistic or NOW Foods.
7. Carlyle Astragalus Root Capsules 4500mg (150 Capsules)
Budget-Friendly & Potent Astragalus Supplement
Why It Stands Out:
- 4,500mg per serving for a strong daily dose
- Non-GMO, gluten-free, and vegetarian-friendly
- Affordable compared to competitors offering similar potency
Carlyle Astragalus provides a strong dose per serving at a lower cost, making it a solid option for those who want higher milligram strength without paying a premium.
Pros:
✔ High potency per serving at 4,500mg
✔ Cost-effective compared to similar-strength supplements
✔ Lab-tested for purity and potency
Cons:
✘ Not standardized for polysaccharide content
✘ Strength is based on raw astragalus root equivalent, not extract
Users report improved energy, immune defense, and respiratory support, especially during seasonal transitions. However, some wish for clearer transparency on the extraction method.
8. Gaia Herbs Astragalus Supreme (120 Liquid Phyto-Capsules)
Premium Liquid Herbal Extract for Maximum Absorption
Why It Stands Out:
- Liquid-filled capsules ensure superior bioavailability
- Blended with Schisandra berry and Ligustrum for added adaptogenic support
- Vegan, gluten-free, and purity-tested
Gaia Herbs’ liquid phyto-capsules make it one of the most bioavailable astragalus supplements available. This formulation is particularly helpful for stress management and energy balance, thanks to the added Schisandra berry and Ligustrum.
Pros:
✔ Liquid formulation absorbs faster than dry capsules
✔ Includes additional adaptogens for stress and energy support
✔ High-quality, sustainably sourced herbal ingredients
Cons:
✘ Expensive compared to other brands
✘ Lower astragalus concentration than pure extracts
Many users swear by its effectiveness for reducing fatigue and supporting immune function. The liquid formulation is especially beneficial for those with digestive issues, as it absorbs more efficiently than traditional capsules.
9. Zazzee Astragalus Extra Strength 5000mg (180 Capsules)
High-Strength 20:1 Extract with 70% Polysaccharides
Why It Stands Out:
- 5000mg equivalent per capsule via a 20:1 extract
- Standardized to 70% polysaccharides—one of the highest concentrations available
- Natural, vegan, and free from common allergens
Zazzee offers one of the strongest astragalus extracts on the market, ensuring a highly potent immune-support formula. The 20:1 extraction ensures that each capsule delivers the equivalent of 5000mg of raw astragalus root while focusing on polysaccharide-rich content.
Pros:
✔ Ultra-concentrated formula—fewer capsules needed per day
✔ One of the highest standardized polysaccharide contents (70%)
✔ Long-lasting 6-month supply (180 capsules)
Cons:
✘ Extract-based formula lacks full-spectrum raw root benefits
✘ Higher price due to extreme potency
This supplement is highly rated for its immune-strengthening properties, with many users noticing increased energy and improved seasonal defense. It’s ideal for those looking for a powerful extract rather than whole-root capsules.
10. NusaPure Astragalus 15,000mg (200 Capsules)
Maximum Strength 30:1 Extract
Why It Stands Out:
- 30:1 extract—the most concentrated on this list
- 15,000mg equivalent per capsule
- Vegan, non-GMO, and manufactured in a cGMP-certified facility
For those who want the highest potency possible, NusaPure’s 30:1 extract provides the equivalent of 15,000mg of astragalus root per capsule. This makes it an excellent choice for those who need a powerful boost in immune function and cardiovascular health.
Pros:
✔ Highest extraction ratio available (30:1)
✔ Super potent dose—ideal for advanced users
✔ 200 capsules provide a nearly 7-month supply
Cons:
✘ May be too strong for those new to astragalus supplementation
✘ Higher extract concentration means a more refined, rather than whole-plant, approach
Users who require a strong immune boost or advanced cardiovascular support appreciate the convenience of a high-dose capsule. However, beginners should start with a lower-potency option before committing to such a strong formula.
Final Verdict: The Best Astragalus Supplement for Your Needs
For general immune support, a 500–1000mg daily dose of a standardized extract (70% polysaccharides) is ideal. If you’re seeking maximum potency, high-ratio extracts like 10:1, 20:1, or 30:1 provide stronger effects. Whole-root powders offer a balanced, full-spectrum approach for those who prefer traditional herbal benefits.
Our Top Picks:
- Best for Immune Support: NOW Foods Astragalus (70% polysaccharides)
- Best High-Potency Extract: Zazzee Astragalus 5000mg (70% polysaccharides)
- Best Whole-Root Option: Nature’s Way Astragalus
- Best Liquid Extract: Gaia Herbs Astragalus Supreme
- Best Budget Option: Carlyle Astragalus 4500mg
How to Take Astragalus for Maximum Benefits
1. For Immune Support
- Standard dose: 500–1000mg per day
- Best type: Extracts with 70% polysaccharides
- When to take: Morning or midday for sustained immunity
2. For Anti-Aging & Longevity
- Standard dose: 1000–5000mg per day
- Best type: High-ratio extract (10:1 or higher)
- When to take: With meals to enhance absorption
3. For Cardiovascular Health
- Standard dose: 1000mg per day
- Best type: Whole-root or standardized extract
- When to take: Split into two doses (morning & evening)
4. For Energy & Endurance
- Standard dose: 500–2000mg per day
- Best type: Liquid or capsule-based adaptogenic blends
- When to take: 30 minutes before exercise or in the morning
FAQs about The Best Astragalus Supplements
1. How long does it take for astragalus to work?
Most people notice improvements in immunity, energy, or endurance within 2–4 weeks. For chronic conditions, benefits may take 2–3 months to become fully noticeable.
2. Can I take astragalus every day?
Yes! Astragalus is safe for long-term use when taken within the recommended dosage range.
3. Does astragalus interact with medications?
Yes. It can interact with immune-suppressing drugs, blood thinners, and diuretics. Always check with a doctor before adding it to your routine.
4. Can I take astragalus with other adaptogens?
Absolutely! It pairs well with:
- Reishi mushroom (for immune & longevity support)
- Rhodiola (for stress resilience & energy)
- Ginseng (for enhanced vitality & performance)
5. What’s the best time of day to take astragalus?
- Morning or midday for immune support & energy
- With meals for better absorption
- Before exercise for endurance benefits
6. Is astragalus suitable for children?
Astragalus has been traditionally used in herbal medicine for children’s immune support, but dosages should be lower than those for adults. Some pediatric herbal formulations include astragalus, but it’s best to consult a pediatrician or herbalist before giving it to children, especially in supplement form.
7. Can astragalus help with seasonal allergies?
Yes! Astragalus contains natural antihistamine properties and may help modulate immune responses, making it a useful supplement for allergy relief. Studies suggest that it may reduce inflammation in the respiratory tract, making seasonal allergies less severe over time.
8. What’s the difference between astragalus root powder and standardized extract?
- Whole-root powder provides a full-spectrum of compounds, including polysaccharides, flavonoids, and saponins, but in lower concentrations. It’s ideal for those who prefer traditional herbal benefits.
- Standardized extracts (e.g., 70% polysaccharides) concentrate active compounds, offering higher potency in smaller doses, making them better suited for targeted immune or cardiovascular support.
9. Can I take astragalus if I have high blood pressure?
Astragalus has been studied for its potential cardiovascular benefits, including its ability to support healthy blood pressure levels. However, it may interact with certain blood pressure medications. If you’re on medication, speak with your doctor before adding astragalus to your regimen.
10. Does astragalus boost energy and endurance?
Yes! As an adaptogen, astragalus helps the body combat stress and fatigue, making it popular among athletes and active individuals. Some research suggests that it can enhance mitochondrial function, which plays a role in energy production and endurance performance.
